Blood-Brain Barrier and Drug Delivery to the CNS

This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain the book covers the latest research on the blood-brain barrier the current problems of and solutions to drug delivery to the central nervous system (CNS) existing strategies and prospects for future research.<br>Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques. <br>A concise reference with reviews from nearly 40 international specialists in diverse fields The Blood-Brain Barrier and Drug Delivery to the CNS<br><li>assesses the properties of the blood-brain barrier to determine and measure drug permeability in animals and humans <br></li><li>presents techniques to predict successful drug uptake through in vitro systems or by computation of physicochemical parameters <br></li><li>examines the multidrug resistance protein P-glycoprotein as a natural transporter <br></li><li>analyzes current drug designs to known requirements for transport <br></li><li>looks at drug delivery systems for the brain <br></li><li>and much more!<br>Densely packed with over 800 literature references drawings photographs x-rays tables and equations The Blood-Brain Barrier and Drug Delivery to the CNS is a vital addition to the bookshelves of biochemists pharmacists clinical and research pharmacologists neuroscientists and neurologists and graduate and medical school students in these disciplines.</li>